Efficacy of 532-nm Q-switched Nd:YAG Laser in the Treatment of Lip Melanosis

J Cutan Aesthet Surg. 2021 Apr-Jun;14(2):203-207. doi: 10.4103/JCAS.JCAS_7_20.

Abstract

Introduction: Lip pigmentation is frequently encountered in the Dermatology outpatient department. No effective treatment is available so far. Topical treatment requires longer time and is often unsatisfactory.

Aim: The aim of this work was to study the efficacy of 532-nm Q-switched Nd:YAG laser in the treatment of lip melanosis.

Settings and design: This was a prospective interventional study.

Materials and methods: Twenty patients in the age group 27-53 years were included in the study. Eight patients had diffuse pigmentation and twelve patients had focal pigmentation. Test spot was done. After topical anesthesia, Q-switched Nd:YAG laser was used. Treatment interval was 4 weeks. Follow-up was done at 1 week and then monthly.

Statistical analysis used: Wilcoxon signed ranks test and P value.

Results: Seven patients (35%) showed an excellent response with more than 75% of pigment clearance. Seven patients (35%) showed a good response, two patients (10%) moderate response, and two patients (10%) had a mild response. Two patients had recurrence after 3 months follow-up. The average number of sessions required for clearance of pigmentation was 2.5. No scarring was seen.

Conclusion: 532-nm Q-switched Nd:YAG laser is safe and effective in the management of lip pigmentation and gives rapid results.

Keywords: Dark lips; Nd; Q-switched; YAG; laser; lip pigmentation.