High throughput molecularly imprinted polymers based electrochemical nanosensors for point-of-care diagnostics of COVID-19

Ayushi Singhal; Arpana Parihar; Neeraj Kumar; Raju Khan

doi:10.1016/j.matlet.2021.130898

High throughput molecularly imprinted polymers based electrochemical nanosensors for point-of-care diagnostics of COVID-19

Mater Lett. 2022 Jan 1:306:130898. doi: 10.1016/j.matlet.2021.130898. Epub 2021 Sep 20.

Authors

Ayushi Singhal^{1

2}, Arpana Parihar¹, Neeraj Kumar^{1

2}, Raju Khan^{1

2}

Affiliations

¹ Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal-462026, MP, India.
² Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Abstract

The importance of early diagnosis of infectious disease has been revealed well by the COVID-19 pandemic. The current methods for testing SARS-CoV-2 mainly utilize biorecognition elements. The process of production of these biorecognition elements is not only tedious, time-consuming but also costly. The molecularly imprinted polymers recently have gained considerable attention as they are stable and also offer high selectivity and specificity than conventional labels. The present review discussed the MIPs-based electrochemical nano-sensors diagnostic of SARS-CoV-2.

Keywords: Biorecognition elements; Electrochemical Sensors; Fabrication; Molecularly Imprinted Polymer; SARS-CoV-2.