Chronic 3D Vascular-Immune Interface Established by Coculturing Pressurized Resistance Arteries and Immune Cells

Hypertension. 2021 Nov;78(5):1648-1661. doi: 10.1161/HYPERTENSIONAHA.121.17447. Epub 2021 Sep 27.

Authors

Daniela Carnevale^{1

2}, Lorenzo Carnevale², Sara Perrotta¹, Fabio Pallante², Agnese Migliaccio², Daniele Iodice², Marialuisa Perrotta¹, Giuseppe Lembo^{1

2}

Affiliations

¹ Department of Molecular Medicine, "Sapienza University" of Rome, Italy (D.C., S.P., M.P., G.L.).
² Unit of Neuro and Cardiovascular Pathophysiology, IRCCS Neuromed, Pozzilli (IS), Italy (D.C., L.C., F.P., A.M., D.I., G.L.).

Abstract

[Figure: see text].

Keywords: arteries; blood pressure; chemotaxis; inflammation; phenotype.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Angiotensin II / pharmacology
Animals
Cell Movement
Coculture Techniques
Female
Hypertension / etiology*
Hypertension / immunology
Male
Mesenteric Arteries / immunology
Mesenteric Arteries / physiology*
Mice
Mice, Inbred C57BL
Organ Culture Techniques
Sex Characteristics
T-Lymphocytes / immunology
T-Lymphocytes / physiology*
Vascular Resistance

Substances

Angiotensin II