The effect of the COVID-19 pandemic on metabolic control in children with type 1 diabetes: a single-center experience

J Pediatr Endocrinol Metab. 2021 Sep 27;35(2):191-195. doi: 10.1515/jpem-2021-0509. Print 2022 Feb 23.

Abstract

Objectives: Coronavirus disease 2019 has caused a major epidemic worldwide, and lockdowns became necessary in all countries to prevent its spread. This study aimed to evaluate the effects of staying-at-home practices on the metabolic control of children and adolescents with type 1 diabetes during the pandemic period.

Materials and methods: Eighty-nine patients younger than 18 years old who were diagnosed with type 1 diabetes at least one year before the declaration of the pandemic were included in the study. The last visit data of the patients before and after the declaration of the pandemic, and the frequency of presentation of diabetes-related emergencies from one year after diagnosis of type 1 diabetes to the declaration of the pandemic, and from the declaration of the pandemic to the last visit after the pandemic declaration were compared.

Results: The total number of patients was 89, and 48 (53.9%) were boys. The mean (± standard deviation [SD]) age at diagnosis was 8.4 ± 3.7 years (boys 7.9 ± 3.6 years; girls 8.9 ± 3.9 years). There was no statistically significant difference when the SD values of the anthropometric measurements, and the glycosylated hemoglobin (HbA1c) and lipid profile tests were compared. However, the frequency of admission to the emergency service related to diabetes was significantly different.

Conclusions: Although the pandemic did not significantly affect the metabolic and glycemic controls of the children with type 1 diabetes included in this study, an increase in the frequency of diabetes-related emergency admissions was noted.

Keywords: COVID-19 pandemic; glycemic control; metabolic control; type 1 diabetes.

MeSH terms

  • Adolescent
  • Age of Onset
  • Anthropometry
  • Body Weight
  • COVID-19*
  • Child
  • Child, Preschool
  • Diabetes Complications / epidemiology
  • Diabetes Mellitus, Type 1 / diet therapy
  • Diabetes Mellitus, Type 1 / metabolism*
  • Diabetes Mellitus, Type 1 / therapy*
  • Exercise Therapy
  • Female
  • Glycated Hemoglobin / analysis
  • Glycemic Control*
  • Humans
  • Lipids / blood
  • Male
  • Pandemics*
  • Patient Compliance

Substances

  • Glycated Hemoglobin A
  • Lipids