18F-FDG-Detected Brown Tumor Confined to the Maxillary Bone With Parathyroid Adenoma

Clin Nucl Med. 2022 Mar 1;47(3):236-238. doi: 10.1097/RLU.0000000000003897.

Abstract

Brown tumor is a reactive osteolytic lesion associated with hyperparathyroidism and an extremely rare form of a single lesion in the maxilla. We report the case of a 57-year-old woman with renal dysfunction, nasal obstruction, and hypercalcemia. MRI and CT revealed a huge osteolytic lesion in the maxilla. 18F-FDG PET/CT demonstrated marked FDG uptake within the mass and the lower-left lobe of the thyroid gland. 99mTc-methoxy-isobutyl-isonitrile scintigraphy suggested that this accumulation was a parathyroid adenoma. Parathyroid adenoma resection was performed, and the maxillary tumor was diagnosed as brown tumor. FDG PET/CT was helpful in evaluating brown tumor and detecting parathyroid adenoma.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Maxilla
  • Middle Aged
  • Osteitis Fibrosa Cystica* / diagnostic imaging
  • Parathyroid Neoplasms* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography

Substances

  • Fluorodeoxyglucose F18