Intercomparison of Geant4 low energy electromagnetic models in 90Y dosimetry

Appl Radiat Isot. 2021 Dec:178:109938. doi: 10.1016/j.apradiso.2021.109938. Epub 2021 Sep 20.

Abstract

This work shows the comparison between Geant4 low energy electromagnetic physics lists G4EmLi-vermorePhysics, G4EmPenelopePhysics, G4EmLowEPPhysics, and G4EmDNAPhysics_option2 when simulating the energy deposition of low mono-energetic electrons and β- emitted from 90Y isotope. The simulation time and influence of production cut were considered. In the sense of balance between the accuracy and computer resource, G4EmPenelopePhysics can be proposed as the best physics model for our future Treatment Planning System (TPS) for treating liver cancer using 90Y microsphere radioembolization therapy.

Keywords: Geant4; Low energy electromagnetic models; Yttrium-90 radioembolization.

MeSH terms

  • Electromagnetic Phenomena*
  • Models, Theoretical*
  • Physical Phenomena
  • Radiometry / methods*
  • Radiotherapy Planning, Computer-Assisted / methods
  • Yttrium Radioisotopes / analysis*

Substances

  • Yttrium Radioisotopes
  • Yttrium-90