Antibiotics and antibiotic resistance genes (ARGs) in the aquatic environment have raised great concerns, as the deleterious effects of residual antibiotics and the emergence of ARGs are challenges to aquaculture. This study analyzed feed, water, sediment and prawns' tissues from six culture ponds (integrated culture: rice-prawn pond; monoculture: prawn pond) in Tianjin, Northeast China. Eighteen types of antibiotics were detected in all ponds, which conferring to four classes of antibiotics including sulfonamides, tetracyclines, fluoroquinolones, macrolides. The mean log bioaccumulation factor (BAF) values for five antibiotics were analyzed in the hepatopancreas, muscle, and plasma, and we found the maximum Log BAF (1.45) for enrofloxacin in prawn plasma. Correlation analysis of antibiotic concentrations between the plasma and the other two tissues indicated that enrofloxacin, norfloxacin, and erythromycin levels in the hepatopancreas and muscle can be predicted by their plasma concentrations. We also conducted a hazard quotient analysis and found that the risk to human health of eating antibiotic-exposed prawns from the two types of aquaculture method was relatively low. Compared with monoculture, rice-prawn co-culture could significantly decrease the abundance of ARGs; additionally, significant correlations were detected among ARGs, antibiotics, and non-antibiotic environmental factors (e.g., total nitrogen, total ammonia nitrogen, and chemical oxygen demand) in prawn. The present study indicated that the rice-prawn co-culture system is more effective than monoculture for mitigating the bioaccumulation of antibiotics and the occurrence of ARGs in prawn.
Keywords: Antibiotic; Antibiotic resistance genes; Aquaculture; Cultured prawn; Health risk; Tissue.
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