A review on allopathic and herbal nanofibrous drug delivery vehicles for cancer treatments

Tarun Mateti; Surabhi Aswath; Anoop Kishore Vatti; Agneya Kamath; Anindita Laha

doi:10.1016/j.btre.2021.e00663

A review on allopathic and herbal nanofibrous drug delivery vehicles for cancer treatments

Biotechnol Rep (Amst). 2021 Aug 5:31:e00663. doi: 10.1016/j.btre.2021.e00663. eCollection 2021 Sep.

Authors

Tarun Mateti¹, Surabhi Aswath¹, Anoop Kishore Vatti¹, Agneya Kamath¹, Anindita Laha¹

Affiliation

¹ Department of Chemical Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal - 576104, Udupi, Karnataka, India.

Abstract

Drug delivery empowered with nanotechnology manifests to be a superior therapy to cancer. Electrospun nanofibers cocooning anti-cancerous drugs have shown tremendous cytotoxicity towards various tumor cells, including breast, brain, liver, and lung cancer cells. This pristine drug delivery system, according to literature, desists showing any undesirable effects on other parts of the body and bestows several other benefits. From nature-derived Curcumin to laboratory-made Doxorubicin, literature proclaims many such drugs used in nanofibrous drug delivery. Also, multi-drug delivery has been reported to exhibit enhanced properties. The present review exhibits the unrealized potential of nanofibrous drug delivery in chemotherapy.

Keywords: Allopathic drug; Cancer; Electrospinning; Herbal drug; Nanofibers; Nanotechnology.

Publication types

Review