Research Progress on Polydopamine Nanoparticles for Tissue Engineering

Yanmei Tang; Yu Tan; Kaili Lin; Min Zhu

doi:10.3389/fchem.2021.727123

Research Progress on Polydopamine Nanoparticles for Tissue Engineering

Front Chem. 2021 Sep 6:9:727123. doi: 10.3389/fchem.2021.727123. eCollection 2021.

Authors

Yanmei Tang¹, Yu Tan², Kaili Lin¹, Min Zhu¹

Affiliations

¹ Department of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology, Shanghai, China.
² Second Dental Clinic, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology, Shanghai, China.

Abstract

Tissue engineering is an interdisciplinary field that aims to develop biological substitutes for the replacement, repair, or enhancement of tissue function. The physical and chemical characteristics of biomaterials exert a profound influence on the biological responses and the following biofunction. Nanostructured coatings have been widely applied as an effective surface modification strategy to improve the bioactivity of biomaterials. Especially, polydopamine and polydopamine-derived nanoparticles are found with excessive adhesiveness, redox activity, photothermal conversion capacity, paramagnetism and conductivity other than excellent biocompatibility, and hydrophilicity. In this article, advances about polydopamine nanoparticles in tissue engineering applications are reviewed, including the repair of bone, cartilage, skin, heart, and nerve, to provide strategies for future biomaterial design.

Keywords: biofunction; nanoparticles; polydopamine; tissue engineering; tissue regeneration.

Publication types

Review