Magnetically Controlled Growing Rods for Early Scoliosis Treatment in Coffin-Siris Syndrome: Case Report and Literature Review

Valerio Andreozzi; Giorgio Princi; Luca Labianca; Domiziana Rinaldi; Andrea Ferretti

Magnetically Controlled Growing Rods for Early Scoliosis Treatment in Coffin-Siris Syndrome: Case Report and Literature Review

Iowa Orthop J. 2021;41(1):55-59.

Authors

Valerio Andreozzi¹, Giorgio Princi¹, Luca Labianca¹, Domiziana Rinaldi², Andrea Ferretti¹

Affiliations

¹ Department of Orthopaedic Surgery, Sapienza University of Rome, Rome, Italy.
² Department of Neuroscience Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome, Rome, Italy.

PMID: 34552404
PMCID: PMC8259188

Abstract

Coffin-Siris Syndrome (CSS) is a rare, genetic syndrome characterized by multiple anomalies, including scoliosis. However, there are only a few reports about the management of scoliosis in these patients. We present the case of an 8-year-old female with CSS presenting with a progressive, rigid thoracolumbar kyphoscoliosis. She was successfully treated with a magnetically controlled growing rod, demonstrating improved ambulatory capacity and performance of activities of daily living. In pediatric patients with Coffin-Siris syndrome, magnetic expandable rods can be considered as an option for the management of progressive early-onset scoliosis. Level of Evidence: V.

Keywords: Coffin-Siris; MAGEC; children; early onset scoliosis; magnetically controlled growing rods.

Publication types

Case Reports
Review

MeSH terms

Abnormalities, Multiple*
Activities of Daily Living
Child
Face / abnormalities
Female
Hand Deformities, Congenital
Humans
Intellectual Disability
Micrognathism*
Neck / abnormalities
Scoliosis* / surgery

Supplementary concepts

Coffin-Siris syndrome