An Overview of Synthesis and Biological Activity of Dihydropyrimidine Derivatives

Abstract

Dihydropyrimidine derivatives are the most important scaffolds due to structural similarities with natural products; it is a heterocyclic compound. The chemistry of Dihydropyrimidine is a growing field. Various reaction schemes for the preparation of Dihydropyrimidines produce different biological effects and offer vast scope in the field of medicinal chemistry. This article's goal is to analyze the work that reported the recent chemistry and pharmacological activities of dihydropyrimidine derivatives.

Keywords: Dihydropyrimidine; anticancer; antimicrobial; antiviral; bignelli reaction; synthesis.