Stem cell-derived exosomes: A supernova in cosmetic dermatology

J Cosmet Dermatol. 2021 Dec;20(12):3812-3817. doi: 10.1111/jocd.14438. Epub 2021 Sep 18.

Abstract

Introduction: Stem cell-derived exosomes are cell-free vesicles secreted by stem cells. Exosomes play a pivotal role in cell-to cell communication due to the functional proteins and genetic information which they carry. In addition, studies on cell migration, tumor invasion, tissue regeneration, myocardial repair after injury, and fracture healing have been widely reported.

Objectives: The purpose of this review is to sum up the current state of research on multiple stem cell-derived exosomes in cosmetic dermatology and to discuss the current challenges and future directions.

Methods: We searched "skin" and "exosome" from PubMed to find the application of stem cell exosomes in cosmetic dermatology.

Results: We found that stem cell-derived exosomes have an important place in skin cosmetology such as wound healing, skin aging, and scar formation.

Conclusion: Stem cell derived exosomes supply a potential tool to cosmetic dermatology. The performance of stem cell derived exosomes in regulating skin physiological and pathobiological functions suggests that stem cell derived exosomes have potential in cosmetic dermatology.

Keywords: cosmetic dermatology; exosome; stem cell-derived.

Publication types

  • Review

MeSH terms

  • Dermatology*
  • Exosomes*
  • Mesenchymal Stem Cells*
  • Stem Cells
  • Wound Healing