Synthesis of 14 beta-cholesta-5,7-dien-3 beta-ol

M Anastasia; P Allevi; P Ciuffreda; A Fiecchi; A Scala

doi:10.1016/0039-128x(87)90094-8

Synthesis of 14 beta-cholesta-5,7-dien-3 beta-ol

Steroids. 1987 Jun;49(6):543-52. doi: 10.1016/0039-128x(87)90094-8.

Authors

M Anastasia¹, P Allevi, P Ciuffreda, A Fiecchi, A Scala

Affiliation

¹ Dipartimento di Chimica e Biochimica Medica, Facoltà di Medicina e Chirurgia, Università di Milano, Italy.

PMID: 3453563
DOI: 10.1016/0039-128x(87)90094-8

Abstract

5,7-Cholestadien-3 beta-ol was transformed into 14 beta-cholesta-5,7-dien-3 beta-ol in six steps. The inversion of the stereochemistry at C-14 was obtained by a selective protection of the delta 5 and the elaboration of the delta 7 double bond.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chemical Phenomena
Chemistry
Cholestadienols / chemical synthesis*
Dehydrocholesterols / chemical synthesis*
Methods
Stereoisomerism

Substances

Cholestadienols
Dehydrocholesterols