Short-Latency Covert Saccades - The Explanation for Good Dynamic Visual Performance After Unilateral Vestibular Loss?

Julia Sjögren; Mikael Karlberg; Craig Hickson; Måns Magnusson; Per-Anders Fransson; Fredrik Tjernström

doi:10.3389/fneur.2021.695064

Short-Latency Covert Saccades - The Explanation for Good Dynamic Visual Performance After Unilateral Vestibular Loss?

Front Neurol. 2021 Aug 31:12:695064. doi: 10.3389/fneur.2021.695064. eCollection 2021.

Authors

Julia Sjögren¹, Mikael Karlberg¹, Craig Hickson², Måns Magnusson¹, Per-Anders Fransson¹, Fredrik Tjernström¹

Affiliations

¹ Department of Clinical Sciences, Otorhinolaryngology Head and Neck Surgery, Skåne University Hospital, Lund University, Lund, Sweden.
² Department of Otorhinolaryngology Head and Neck Surgery, William Harvey Hospital, East Kent Hospitals University Foundation Trust, Ashford, United Kingdom.

Abstract

Background: Functional head impulse test (fHIT) tests the ability of the vestibulo-ocular reflex (VOR) to allow visual perception during head movements. Our previous study showed that active head movements to the side with a vestibular lesion generated a dynamic visual performance that were as good as during movements to the intact side. Objective: To examine the differences in eye position during the head impulse test when performed with active and passive head movements, in order to better understand the role of the different saccade properties in improving visual performance. Method: We recruited 8 subjects with complete unilateral vestibular loss (4 men and 4 women, mean age 47 years) and tested them with video Head Impulse Test (vHIT) and Functional Head Impulse Test (fHIT) during passive and active movements while looking at a target. We assessed the mean absolute position error of the eye during different time frames of the head movement, the peak latency and the peak velocity of the first saccade, as well as the visual performance during the head movement. Results: Active head impulses to the lesioned side generated dynamic visual performances that were as good as when testing the intact side. Active head impulses resulted in smaller position errors during the visual perception task (p = 0.006) compared to passive head-impulses and the position error during the visual perception time frame correlated with shorter latencies of the first saccade (p < 0.001). Conclusion: Actively generated head impulses toward the side with a complete vestibular loss resulted in a position error within or close to the margin necessary to obtain visual perception for a brief period of time in patients with chronic unilateral vestibular loss. This seems to be attributed to the appearance of short-latency covert saccades, which position the eyes in a more favorable position during head movements.

Keywords: compensation; covert saccades; functional head impulse test; position error; saccades; vestibular loss; video head impulse test; visual performance.