Peripheral pulmonary mucous gland adenoma with a cavity mimicking lung cancer

Gen Thorac Cardiovasc Surg. 2022 Jan;70(1):92-95. doi: 10.1007/s11748-021-01705-2. Epub 2021 Sep 15.

Abstract

A 71-year-old woman presented to our hospital because of a 10 mm nodule with a cavity in right lower lobe on chest computed tomography. Fluorodeoxyglucose-positron emission tomography showed slight accumulation in the nodule (maximum standard uptake value 2.08). Her serum carcinoembryonic antigen concentration was 5.4 ng/mL. Wedge resection of the tumor was performed for diagnostic and treatment purposes. Findings on intraoperative pathological examination of a frozen section were suspicious for adenocarcinoma. We, therefore, performed a right lower lobectomy and mediastinal lymph node dissection. Postoperative histological examination revealed a mucous gland adenoma. The patient's postoperative course was favorable and she was discharged 7 days after surgery. Four months later, the serum carcinoembryonic antigen concentration had decreased to 3.1 ng/mL. Pulmonary mucous gland adenomas are rarely located peripherally. These benign tumors should be considered, even in the presence of high serum carcinoembryonic antigen concentrations or increased fluorodeoxyglucose uptake on fluorodeoxyglucose-positron emission tomography.

Keywords: Carcinoembryonic antigen; Fluorodeoxyglucose-positron emission tomography; Mucous gland adenoma; Surgery.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / diagnostic imaging
  • Adenocarcinoma* / surgery
  • Adenoma* / diagnostic imaging
  • Adenoma* / surgery
  • Aged
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Lung Neoplasms* / diagnostic imaging
  • Lung Neoplasms* / surgery
  • Positron-Emission Tomography

Substances

  • Fluorodeoxyglucose F18