An Adrenocortical Carcinoma Evolving After Nine Years of Latency From a Small Adrenal Incidentaloma

Cureus. 2021 Aug 3;13(8):e16851. doi: 10.7759/cureus.16851. eCollection 2021 Aug.

Abstract

Adrenal incidentalomas (AIs) are common incidental findings in medical practice with clinical significance. Although most AIs are nonsecretory and nonmalignant, they require a short course of follow-up over one to two years to rule out malignancy or hormonal secretion according to clinical practice guidelines. However, this can result in some adrenocortical carcinomas (ACCs) being missed if they transform at a later stage or evolve slowly. Here, we report one such case of an AI, which although remained indolent, eventually transformed into an ACC many years after the initial detection.

Keywords: adrenal carcinoma; adrenal disease; adrenal disorders; adrenal incidentaloma; adrenal pheochromocytoma; adrenal surgery; benign adrenal tumor; clinical guidelines; indeterminate adrenal nodule; secretory tumors of adrenal gland.

Publication types

  • Case Reports