Nanotechnology-Based Approach to Combat Pandemic COVID 19: A Review

Macromol Symp. 2021 Jun;397(1):2000336. doi: 10.1002/masy.202000336. Epub 2021 Jun 17.

Abstract

The emergence of a novel Corona virus (COVID 19) originated on December 19 from China. The city of Wuhan, the capital city of Hubei province, China, is responsible for an outbreak of respiratory illness known as COVID 19 and it has been rapidly spread across the world claiming millions of lives. The sudden outbreak of novel Coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or 2019-nCoV), is a big concern for their speedy mitigation using the predictable treatment and creating its approach around the world. Researchers and doctors are in search of rapid diagnosis kit, drugs, and viral-resistant personal protective equipment (PPE) to clinical diagnosis, medication, and prevent the spread of COVID 19. A rational approach with adaptability and broad viewpoint to challenge the growing pain could be overcome by the application of appropriate technology. The nanotechnology-based approach can significantly serve the purpose of the current pandemic situation of COVID 19. But same time implementation of innovative and creative nanotech approach, there is a decisive need for the full knowledge of SARS-CoV-2 pathogenesis. Moreover, to defeat COVID 19, particularly nanotech-based system with their viral inhibitory properties to increase the effective nanotech approach is essential. In this scenario, this review aims to summarize the past, present, and future of nanotech-based systems that can be used to treat COVID 19, highlighting Nano-based compounds. Lastly, the potential application of the different category of Inorganic Nanomaterials/Inorganic organic conjugate /hybrid system and their practical applicability as suitable means for inspiring against COVID 19 has also been discussed.

Keywords: 2019‐nCoV; COVID 19; SARS‐CoV; antiviral agents; coronavirus; nanoparticles; nanotechnology; therapeutics and diagnosis.