Time-dependent Diffusion in Brain Abscesses Investigated with Oscillating-gradient Spin-echo

Magn Reson Med Sci. 2022 Oct 1;21(4):525-530. doi: 10.2463/mrms.ici.2021-0083. Epub 2021 Sep 10.

Abstract

Oscillating-gradient spin-echo sequences enable the measurement of diffusion weighting with a short diffusion time and can provide indications of internal structures. We report two cases of brain abscess in which the apparent diffusion coefficient (ADC) values appear higher at short diffusion times in comparison with those at long diffusion times. Diffusion time dependence of the ADC in brain abscesses suggests not only substrate viscosity but also restricted diffusion due to the structure within the lesions.

Keywords: brain abscess; diffusion time; diffusion-weighted imaging; microstructure; oscillating-gradient spin-echo.

MeSH terms

  • Biological Transport
  • Brain Abscess* / diagnostic imaging
  • Diffusion
  • Diffusion Magnetic Resonance Imaging*
  • Humans

Grants and funding

This work was supported in part by JSPS KAKENHI (grant no. 18H02772).