Effect of frailty on physical activity levels and walking capacity in patients with peripheral artery disease: A cross-sectional study

J Vasc Nurs. 2021 Sep;39(3):84-88. doi: 10.1016/j.jvn.2021.07.001. Epub 2021 Jul 29.

Abstract

Background: This study aimed to analyze the effect of frailty on walking capacity and physical activity levels of patients with peripheral artery disease (PAD).

Methods: A cross-sectional study including 216 symptomatic PAD patients (e.g. claudication) was conducted. Moreover, the frailty profile was established, for which six-minute walk test, Walking Impairment Questionnaire (WIQ), and physical activity level were evaluated.

Results: Frailty was prevalent in 13.4%, 72.2%, and 14.4% of frail, pre-frail, and not-frail patients, respectively. Walking capacity was lower in frail patients than in not-frail patients (p < 0.024). The domains of distance and speed of WIQ were lower in frail patients than in not-frail patients, and these domains were also lower in pre-frail than in not-frail patients (p < 0.050 for all). The domain of stairs was lower in frail patients than in not-frail and pre-frail patients (p = 0.016). Physical activity levels were similar among groups (p > 0.050).

Conclusion: Frailty is associated with further walking impairment in patients with PAD.

Keywords: Fitness; Frailty; Intermittent claudication; Peripheral artery disease; Physical activity.

MeSH terms

  • Cross-Sectional Studies
  • Frailty*
  • Humans
  • Intermittent Claudication
  • Peripheral Arterial Disease*
  • Walking