Gender differences in Damp-Heat Syndrome: A review

Biomed Pharmacother. 2021 Nov:143:112128. doi: 10.1016/j.biopha.2021.112128. Epub 2021 Sep 4.

Abstract

Gender differences have important biological significance for medical research. In this study, a bias towards males was identified in animal experiments of Damp-Heat Syndrome in traditional Chinese medicine, as was first proposed by a data mining method. Combined with the correlation between Damp-Heat Syndrome in traditional Chinese medicine and Gender differences, it was considered that Gender-related factors have a significant influence on the development of Damp-Heat Syndrome in traditional Chinese medicine. However, most traditional Chinese medicine studies ignore the key significance of Gender-related factors. This study emphasises that the development of modern traditional Chinese medicine research needs to pay full attention to the biological significance of Gender-related factors and to apply this concept to the research on the Gender equivalence strategy in basic research and the practice of personalised medical diagnosis and clinical treatment.

Keywords: Animal experimental study; Damp-Heat Syndrome; Gender differences; Gender equality; Precision medicine; Syndrome characteristics; TCM Syndrome diseases; Traditional Chinese medicine.

Publication types

  • Review

MeSH terms

  • Animals
  • Data Mining
  • Disease Models, Animal
  • Female
  • Health Status Disparities*
  • Humans
  • Immune System / immunology
  • Immune System / metabolism
  • Immune System / physiopathology*
  • Inflammation / immunology
  • Inflammation / metabolism
  • Inflammation / physiopathology*
  • Inflammation / therapy
  • Inflammation Mediators / metabolism
  • Male
  • Medicine, Chinese Traditional*
  • Risk Factors
  • Sex Characteristics*
  • Sex Factors
  • Syndrome
  • Systems Biology

Substances

  • Inflammation Mediators