Objective: To analyze the literature knowledge structure and acupoint matching rules of acupuncture for depression.
Methods: The articles regarding acupuncture for depression published from January 1 of 1984 to October 19 of 2020 were searched in CNKI database. CiteSpace5.7.R2 software was used to import the literature data, and the keyword cluster analysis, emergence analysis and time-zone analysis of articles and acupoints were conducted, and the map of scientific knowledge was draw.
Results: A total of 3524 articles were included to the knowledge structure analysis, while 601 articles into the acupoint matching rules analysis. There were 13 keyword clusters of acupuncture for depression, with "post-stroke depression" and "electroacupuncture treatment" as high-frequency keywords, and "electroacupuncture treatment" and "Hamilton depression scale" had high centrality, and "electroacupuncture treatment" had the highest emergence intensity. The keywords such as "electroacupuncture treatment" and "Hamilton depression scale", etc. appeared the earliest, followed by "post-stroke depression", "fluoxetine" and "auricular point therapy", etc. According to traditional Chinese medicine theory, acupoint keywords were divided into four clusters: ①core acupoint, ②replenishing-spleen and dispelling phlegm, dispersing-liver and relieving depression, reinforcing qi and nourishing blood, ③back-shu points, five-zhi points, ④inducing-resuscitation and opening-closes.
Conclusion: The main knowledge structure of acupuncture for depression includes five parts: treatment method, depression type, TCM-related diseases, literature type and curative effect index. Clinical acupoint matching should adhere to the principle of "focusing the disease before syndrome" and "combination of disease and syndrome", and treatment should be modified for the syndromes of phlegm stagnation blocking, liver-stagnation and qi-stagnation, and deficiency of both qi and blood.
目的：分析针灸治疗抑郁症文献的知识结构及配穴规律。方法：检索1984年1月1日至2020年10月19日中国期刊全文数据库（CNKI）中针灸治疗抑郁症的文献。利用CiteSpace5.7.R2软件导入文献数据，进行文献及穴位关键词聚类、突现、时区分析，绘制科学知识图谱。结果：纳入3524篇文献研究针灸治疗抑郁症知识结构，复筛后纳入601篇研究穴位配伍规律。针灸治疗抑郁症文献关键词形成13个聚类，其中“中风后抑郁”“电针治疗”为高频关键词，“电针治疗”“汉密尔顿抑郁量表”具有高中心度，“电针治疗”突现强度最高。“电针治疗”“汉密尔顿抑郁量表”等关键词出现时间最早，之后陆续出现“中风后抑郁”“氟西汀”“耳穴疗法”等。针灸治疗抑郁症文献的穴位关键词依据中医理论可分为4个聚类：①核心针穴组，②健脾化痰、疏肝解郁、益气养血加减组，③五脏背俞穴、五志穴组，④醒神启闭针刺法组。结论：针灸治疗抑郁症文献的主要知识结构包括治疗方法、抑郁症类型、中医相关疾病、文献类型及疗效指标5个部分。临床配穴应当秉持先病后证、病证结合的原则，重点针对痰湿阻滞、肝郁气滞、气血两虚3个证型进行加减。.
Keywords: acupuncture and moxibustion; depression; knowledge structure; rules of acupoint matching.