Treatment of radiological contamination: a review

J Radiol Prot. 2021 Nov 10;41(4). doi: 10.1088/1361-6498/ac241b.

Abstract

After nuclear accidents, people can be contaminated internally via ingestion, inhalation and via intact skin or wounds. The assessment of absorbed, committed doses after internal exposure is based on activity measurement byin vivoorin vitrobioassay. Estimation of dose following internal contamination is dependent on understanding the nature and form of the radionuclide. Direct counting methods that directly measureγ-rays coming from within the body or bioassay methods that measure the amount of radioactive materials in urine or feces are used to estimate the intake, which is required for calculating internal exposure doses. The interpretation of these data in terms of intake and the lifetime committed dose requires knowledge or making assumptions about a number of parameters (time, type of exposure, route of the exposure, physical, biological and chemical characteristics) and their biokinetics inside the body. Radioactive materials incorporated into the body emit radiation within the body. Accumulation in some specific organs may occur depending on the types of radioactive materials. Decorporation therapy is that acceleration of the natural rate of elimination of the contaminant will reduce the amount of radioactivity retained in the body. This article presents an overview of treatment of radiological contamination after internal contamination.

Keywords: bioassay methods; decorporation therapy; internal contamination; radionuclide.

Publication types

  • Review

MeSH terms

  • Humans
  • Radiation Dosage
  • Radioactive Hazard Release*
  • Radioisotopes
  • Radiology*

Substances

  • Radioisotopes