Cholangitis in three critically ill patients after a severe CoVID-19 infection

Cyrille Gourjault; Hassan Tarhini; Mayda Rahi; Michael Thy; Diane Le Pluart; Christophe Rioux; Marion Parisey; Sophie Ismael; Ali Al Rida Aidibi; Valerie Paradis; Jade Ghosn; Yazdan Yazdanpanah; François-Xavier Lescure; Anne Gervais

doi:10.1016/j.idcr.2021.e01267

Cholangitis in three critically ill patients after a severe CoVID-19 infection

IDCases. 2021:26:e01267. doi: 10.1016/j.idcr.2021.e01267. Epub 2021 Aug 31.

Authors

Cyrille Gourjault¹, Hassan Tarhini¹, Mayda Rahi¹, Michael Thy¹, Diane Le Pluart¹, Christophe Rioux¹, Marion Parisey², Sophie Ismael¹, Ali Al Rida Aidibi³, Valerie Paradis^{4

5}, Jade Ghosn^{1

6}, Yazdan Yazdanpanah^{1

6}, François-Xavier Lescure^{1

6}, Anne Gervais¹

Affiliations

¹ Service de Maladies Infectieuses et Tropicales, Hôpital Bichat Claude Bernard, AP-HP, 75018 Paris, France.
² Service de maladies infectieuses et tropicale, Hôpital René Dubos, Pontoise, France.
³ Groupe hospitalier intercommunal Montfermeil, France.
⁴ Centre National de la Recherche Scientiﬁque, Formation de Recherche en Evolution, 2443 Paris, France.
⁵ Service d'Anatomie Pathologique, Hôpital Beaujon, Clichy, France.
⁶ Université de Paris, Infection Modelisation Antimicrobial Evolution (IAME), Inserm UMR1137, 75006 Paris, France.

Abstract

Coronavirus disease 2019 (CoVID-19) is a viral disease. Although the predominant presentation is respiratory disease, other manifestations such as gastrointestinal manifestations are commonly reported. Nevertheless, it has not been associated with chronic cholangitis or hepatic injury. In this study, we report three cases of severe CoVID-19 infection that required ICU admission, intubation, and sedation with ketamine. All three patients had abnormal liver function despite recovery and were diagnosed with cholangitis in the context of CoVID-19.

Keywords: Cholangitis; CoVID-19; Hepatobiliary diseases; ICU; Liver transplantation; SARS-CoV-2.

Publication types

Case Reports