High-speed photoacoustic microscopy: A review dedicated on light sources

Soon-Woo Cho; Sang Min Park; Byullee Park; Do Yeon Kim; Tae Geol Lee; Beop-Min Kim; Chulhong Kim; Jeesu Kim; Sang-Won Lee; Chang-Seok Kim

doi:10.1016/j.pacs.2021.100291

High-speed photoacoustic microscopy: A review dedicated on light sources

Photoacoustics. 2021 Aug 6:24:100291. doi: 10.1016/j.pacs.2021.100291. eCollection 2021 Dec.

Authors

Soon-Woo Cho¹, Sang Min Park¹, Byullee Park², Do Yeon Kim^{3

4}, Tae Geol Lee³, Beop-Min Kim^{4

5}, Chulhong Kim², Jeesu Kim¹, Sang-Won Lee^{3

6}, Chang-Seok Kim¹

Affiliations

¹ Department of Cogno-Mechatronics Engineering, Pusan National University, Busan, 46241, Republic of Korea.
² Department of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea.
³ Safety Measurement Institute, Korea Research Institute of Standards and Science, Daejeon, 34113, Republic of Korea.
⁴ Department of Bio-Convergence Engineering, Korea University, Seoul, 02841, Republic of Korea.
⁵ Interdisciplinary Program in Precision Public Health, Korea University, Seoul, 02481, Republic of Korea.
⁶ Department of Medical Physics, University of Science and Technology, Daejeon, 34113, Republic of Korea.

Abstract

In recent years, many methods have been investigated to improve imaging speed in photoacoustic microscopy (PAM). These methods mainly focused upon three critical factors contributing to fast PAM: laser pulse repetition rate, scanning speed, and computing power of the microprocessors. A high laser repetition rate is fundamentally the most crucial factor to increase the PAM speed. In this paper, we review methods adopted for fast PAM systems in detail, specifically with respect to light sources. To the best of our knowledge, ours is the first review article analyzing the fundamental requirements for developing high-speed PAM and their limitations from the perspective of light sources.

Keywords: Fiber laser; High-speed imaging; Light sources; Photoacoustic microscopy.