The "flip-flop" phenomenon may be present in differentiated progressive thyroid cancer. A high suspicion index must be maintained when this phenomenon coexists with a high tumor burden, due to the risk of the appearance of distinct tumors.
Keywords: FDG‐PET/CT; dedifferentiate thyroid cancer; differentiated thyroid cancer; iodine/FDG uptake; radioiodine therapy; radioiodine‐refractory thyroid cancer; “flip‐flop’’ phenomenon.
© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.