Pangasius Fish Skin and Swim Bladder as Gelatin Sources for Hard Capsule Material

Int J Biomater. 2021 Aug 27:2021:6658002. doi: 10.1155/2021/6658002. eCollection 2021.

Abstract

In this paper, we report the extraction and characterization of gelatin from the abundant industrial fishery waste of Pangasius skin and swim bladder and its application as the base material for hard capsule shells. The yield of gelatin ranged between 19 and 23%, content of moisture is 7.6-9.2%, ash is 1.1-1.7%, pH is 4.1-5.2, gel strength is 238-278 bloom, and viscosity is 65-74.7% mP. SDS-PAGE showed all gelatins have chains of α1, α2, and β-peptides. The skin, swim bladder, and mixed gelatins were successfully used in the production of hard capsule shells. The dimensions, weight, disintegration time, and water content properties of the hard capsules from these Pangasius wastes were akin to the standards of commercial capsules.