Psychiatric morbidity in patients with idiopathic Parkinson's disease: A cross-sectional study

Santhosh Kumar; Ajit Avasthi; Manish Modi; Sandeep Grover

doi:10.4103/ipj.ipj_8_21

Psychiatric morbidity in patients with idiopathic Parkinson's disease: A cross-sectional study

Ind Psychiatry J. 2021 Jan-Jun;30(1):165-174. doi: 10.4103/ipj.ipj_8_21. Epub 2021 Jun 24.

Authors

Santhosh Kumar¹, Ajit Avasthi¹, Manish Modi², Sandeep Grover¹

Affiliations

¹ Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
² Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

Objective: To evaluate the prevalence of psychiatric comorbidities in patients with idiopathic Parkinson's disease (IPD).

Methodology: Two hundred and thirty-nine patients with IPD were evaluated on Mini-International Neuropsychiatric Interview PLUS (MINI-PLUS). In addition, patients found to have depression as per the MINI-PLUS were evaluated on Beck Depression Inventory.

Results: One hundred and thirty-five (56.5%) patients had a current psychiatric diagnosis and 59.8% had a lifetime psychiatric diagnosis. As per MINI-PLUS, about two-fifth (39.7%) of patients had suicidality. In 18.8% of patients, suicidality was present in the absence of axis-I psychiatric diagnosis. Among the various psychiatric disorders, the most common disorders included depressive disorders (current: 17.5%; lifetime: 23.8%), anxiety disorders (current: 17.5%; lifetime: 17.5%), and psychotic disorders (current: 11.3%; lifetime: 11.7%).

Conclusions: More than half of the patients with Parkinson's disease have psychiatric disorders. High prevalence of psychiatric morbidity calls for close liaison between the neurologist and the psychiatric disorders.

Keywords: Depression; Parkinson's disease; psychiatric disorders; psychosis; quality of life.