After a number of years of research in the field of miRNA, the robustness and biological relevance of many published articles is increasingly being questioned. We propose the use of new RNA-seq approaches, genome editing technologies, and updated public databases to improve the quality, reliability, and relevance of published data.
Keywords: CRISPR; RNA sequencing; genome editing; microRNA; noncoding RNA.
Copyright © 2021 Elsevier Ltd. All rights reserved.