Testing the Physical and Molecular Effects of Nutritional Supplements and Resistance Exercise in Middle-Aged Females

Methods Mol Biol. 2022:2343:345-360. doi: 10.1007/978-1-0716-1558-4_25.

Abstract

Aging results in loss of muscle mass and strength, which are linked to development of metabolic disorders such as insulin resistance, obesity, and type 2 diabetes mellitus. A number of studies have now shown that these effects can be ameliorated by dietary supplementation with natural products such as vitamins, omega-3 fatty acids, and protein and by physical activities such as aerobic and resistance exercise. Here, we present a protocol for setting up a trial to test the effects of vitamin D and omega-3 fatty acid supplementation and resistance exercise on various anthropometric and molecular measurements in middle-aged females.

Keywords: Metabolism; Obesity; Omega-3 fatty acids; Overweight; Resistance exercise; Vitamin D.

MeSH terms

  • Diabetes Mellitus, Type 2
  • Dietary Supplements
  • Exercise
  • Female
  • Humans
  • Middle Aged
  • Resistance Training*
  • Vitamins / pharmacology

Substances

  • Vitamins