Colorectal cancer is the third most common cancer and accounts for the second highest number of cancer-related deaths worldwide. Natural products such as the turmeric-derived curcuminoids are known to have protective effects against several kinds of cancers by acting as antioxidant and anti-inflammatory agents. Here, we present a protocol for assessing the effects of curcuminoids on serum cytokine profiles in a double-blind placebo-controlled trial of patients with stage 3 colorectal cancer undergoing chemotherapy. The protocol could also be applied to other cancer types.
Keywords: Colorectal cancer; Curcumin; Curcuminoids; Cytokines; Inflammation; Turmeric.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.