Under Pressure: Post-Transplant Lymphoproliferative Disease: A Case of Pulmonary Artery External Compression

Dario Freitas; Maria Buttice; David Wrench; Yaso Emmanuel

doi:10.1016/j.jaccas.2021.05.011

Under Pressure: Post-Transplant Lymphoproliferative Disease: A Case of Pulmonary Artery External Compression

JACC Case Rep. 2021 Aug 19;3(10):1315-1317. doi: 10.1016/j.jaccas.2021.05.011. eCollection 2021 Aug 18.

Authors

Dario Freitas¹, Maria Buttice², David Wrench³, Yaso Emmanuel¹

Affiliations

¹ Department of Cardiology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
² Department of Cellular Pathology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
³ Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

Abstract

Post-transplant lymphoproliferative disorder (PTLD) is an often fatal complication of cardiac transplantation that occurs in 2% to 6% of transplant recipients. We report a case in which PTLD led to pulmonary artery external compression and multimodality imaging showed key features in the diagnosis, management, and follow-up. (Level of Difficulty: Intermediate.).

Keywords: CT, computed tomography; EBV, Epstein-Barr virus; Ig, immunoglobulin; PTLD, post-transplant lymphoproliferative disorder; TAPSE, tricuspid annular plane systolic excursion; TTE, 2-dimensional transthoracic echocardiogram; biopsy; computed tomography; echocardiography; external compression; post-transplant lymphoproliferative disease; pulmonary artery.