Large-Scale Production of Hierarchically Porous Metal-Organic Frameworks by a Reflux-Assisted Post-Synthetic Ligand Substitution Strategy

Guorui Cai; Xing Ma; Meruyert Kassymova; Kang Sun; Meili Ding; Hai-Long Jiang

doi:10.1021/acscentsci.1c00743

Large-Scale Production of Hierarchically Porous Metal-Organic Frameworks by a Reflux-Assisted Post-Synthetic Ligand Substitution Strategy

ACS Cent Sci. 2021 Aug 25;7(8):1434-1440. doi: 10.1021/acscentsci.1c00743. Epub 2021 Aug 6.

Authors

Guorui Cai¹, Xing Ma¹, Meruyert Kassymova¹, Kang Sun¹, Meili Ding¹, Hai-Long Jiang¹

Affiliation

¹ Hefei National Laboratory for Physical Sciences at the Microscale, CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China.

Abstract

The mass production of hierarchically porous metal-organic frameworks (HP-MOFs) with adjustable morphology and size as well as retained crystallinity is highly desirable yet challenging. Herein, we have developed a versatile post-synthetic ligand substitution (PSLS) strategy to convert typical microporous MOFs and even their composites to HP-MOFs and their composites at a 10 g level and beyond in a simple reflux system. The resulting HP-MOFs feature intrinsic micropores and abundant defective mesopores, which greatly facilitate the transport and activation of large substrates for stable and efficient heterogeneous catalysis. Furthermore, the presence of defective mesopores in the HP-MOF composites improves activity and selectivity for large molecule-involved one-pot tandem catalysis. This strategy opens a new door to fast, facile, general, and scale-up production of HP-MOFs and related composites for expanding applications of conventional microporous MOF-based materials.