Commentary on Intraglumerular dysfunction predicts kidney failure in the type 2 diabetes

J Diabetes Investig. 2021 Dec;12(12):2124-2125. doi: 10.1111/jdi.13655. Epub 2021 Sep 22.

Abstract

The key physiological parameters that determine glomerular filtration rate levels are renal plasma flow, filtration fraction, intraglomerular pressure, and balance between afferent and efferent glomerular arteriolar resistance. The evaluation of the balance between afferent and efferent glomerular arteriolar resistance might be useful for the classification of diabetic kidney disease.

MeSH terms

  • Animals
  • Arterioles / physiopathology
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Diabetic Nephropathies / etiology
  • Diabetic Nephropathies / physiopathology*
  • Glomerular Filtration Rate
  • Humans
  • Kidney / physiopathology
  • Kidney Glomerulus / blood supply*
  • Renal Insufficiency / etiology
  • Renal Insufficiency / physiopathology*
  • Vascular Resistance