Age and sex-specific incidence rates of group A streptococcal pharyngitis between 2010 and 2018: a population-based study

Future Microbiol. 2021 Sep:16:1053-1062. doi: 10.2217/fmb-2021-0077. Epub 2021 Sep 1.

Abstract

Aim: Group A streptococcus (GAS) pharyngitis is a common clinical infection with significant morbidity but remains understudied. Materials & methods: We sought to assess the rates of testing and incidence of GAS pharyngitis in Calgary, Alberta based on age and sex. Results: A total of 1,074,154 tests were analyzed (58.8% female, mean age 24.8 years) of which 16.6% were positive. Age-standardized testing and positivity was greatest in the 5-14 years age group and lowest in persons over 75 years. Females had greater rates of testing and positivity throughout. Testing rates (incidence rate ratios: 1.40, 95% CI: 1.39-1.41) and case rates (incidence rate ratios: 1.36, 95% CI: 1.33-1.39) increased over time. Conclusion: Future studies should focus on evaluating disparities in testing and treatment outcomes to optimize the approach to this infection.

Keywords: group A streptococcal pharyngitis; incidence; population health; strep throat.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Canada / epidemiology
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Pharyngitis* / epidemiology
  • Sex Distribution
  • Streptococcal Infections / epidemiology*
  • Young Adult