Reactive oxygen and nitrogen species regulate porcine embryo development during pre-implantation period: A mini-review

Zhen Luo; Jianbo Yao; Jianxiong Xu

doi:10.1016/j.aninu.2021.03.007

Reactive oxygen and nitrogen species regulate porcine embryo development during pre-implantation period: A mini-review

Anim Nutr. 2021 Sep;7(3):823-828. doi: 10.1016/j.aninu.2021.03.007. Epub 2021 Jul 15.

Authors

Zhen Luo¹, Jianbo Yao², Jianxiong Xu¹

Affiliations

¹ School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai Key Laboratory of Veterinary Biotechnology, Shanghai, China.
² Division of Animal and Nutritional Sciences, West Virginia University, Morgantown, WV, USA.

Abstract

Significant porcine embryonic loss occurs during conceptus morphological elongation and attachment from d 10 to 20 of pregnancy, which directly decreases the reproductive efﬁciency of sows. A successful establishment of pregnancy mainly depends on the endometrium receptivity, embryo quality, and utero-placental microenvironment, which requires complex cross-talk between the conceptus and uterus. The understanding of the molecular mechanism regulating the uterine-conceptus communication during porcine conceptus elongation and attachment has developed in the past decades. Reactive oxygen and nitrogen species, which are intracellular reactive metabolites that regulate cell fate decisions and alter their biological functions, have recently reportedly been involved in porcine conceptus elongation and attachment. This mini-review will mainly focus on the recent researches about the role of reactive oxygen and nitrogen species in regulating porcine embryo development during the pre-implantation period.

Keywords: Embryo development; Porcine; Pre-implantation; Reactive oxygen and nitrogen species.

Publication types

Review