Morphometric Study of Mitral Valve Annulus in Iran

Tahereh Mohtaj; Mathias H Aazami; Ghassem Sazegar; Hoorak Poorzand; Aria Hedjazi; Negar Morovatdar; Ahmad Toorabi

doi:10.22086/gmj.v0i0.1078

Morphometric Study of Mitral Valve Annulus in Iran

Galen Med J. 2018 Mar 31:7:e1078. doi: 10.22086/gmj.v0i0.1078. eCollection 2018.

Authors

Tahereh Mohtaj¹, Mathias H Aazami^{2

3}, Ghassem Sazegar^{1

4}, Hoorak Poorzand⁵, Aria Hedjazi⁶, Negar Morovatdar⁷, Ahmad Toorabi⁸

Affiliations

¹ Department of Cell Biology and Anatomy, School of Medicine, Medical Sciences University, Mashhad, Iran.
² Javad Al-Aemeh Heart Hospital, Honarestan Avenue, Mashhad, Iran.
³ Cardiac Anesthesia Research Center, Mashhad University of Medical Sciences, Imam Reza Teaching Hospital, Ibn-Sina Avenue, Mashhad, Iran.
⁴ Macroanatomy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
⁵ Atherosclerosis Prevention Research Center, Department of Cardiology, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
⁶ Legal Medicine Research Center, legal Medicine Organization, Tehran, Iran.
⁷ Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
⁸ Deputy of Culture and Ethics, School of Medicine, Mashhad University of Medical Sciences, Vakil Abad Avenue, Mashhad, Iran.

Abstract

Background: This study aimed to determine the normal dimensions of the mitral annulus (MA) in Iranian population.

Materials and methods: This cross-sectional study was conducted using 88 fresh hearts of male and female cadavers for six months in Mashhad, Iran. Normal data were determined by measuring the exact dimensions of the MA in fresh hearts of patients who had died of non-cardiac causes and considering some parameters such as age, gender, stature, and weight. Images of the valves and leaflets were prepared by marking the anterior (A2, midpoint of anterior) and posterior areas of P1, P2, and P3 using a needle. To analyze the data, SPSS version 16 was used.

Results: The means of anatomic area, anatomic perimeter, inter-commissural distance, A2-P1, A2-P2, A2-P3, Base-P1, Base-P2, Base-P3, and Base-A were 14±1.28, 8.3±1, 2.7±0.42, 2.27±0.37, 2.3±0.43, 2.06±0.35, 1.66±0.43, 1.2±0.97, 1.5±0.66, and 3.2±0.52, respectively. Comparison of the age groups regarding valve leaflets showed that Strut-P1 and Base-P2 were significantly different. Comparison of the valve leaflets and sub-valve indicators between the two genders reflected no significant differences. Age groups differed significantly in terms of Strut-P1 and Base-P2 (P=0.004 and P=00.1, respectively).

Conclusions: A2-P3, A2-P1, anatomic perimeter, and anatomic area were found to be related to gender. A2-P1 and A2-P2 and some leaflet indicators such as Strut-P1 and Base-P2 were associated with age, whereas Base-P2 was affected by body mass index.

Keywords: Cadaver; Cardiac Morphology; Mitral Valve.