Activation of Ca²⁺ -AMPK-mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts

Clin Transl Med. 2021 Aug;11(8):e521. doi: 10.1002/ctm2.521.

Authors

Dasol Kim¹, Kyeong Eun Yang², Dong Won Kim¹, Hui-Yun Hwang¹, Jinyoung Kim¹, Jong-Soon Choi³, Ho Jeong Kwon¹

Affiliations

¹ Chemical Genomics Leader/Global Research Laboratory, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
² Bio-Chemical Analysis Group, Center for Research Equipment, Korea Basic Science Institute, Daejeon, Republic of Korea.
³ Research Center for Materials Analysis, Korea Basic Science Institute, Daejeon, Republic of Korea.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

AMP-Activated Protein Kinases / metabolism*
Animals
Antineoplastic Agents, Phytogenic / metabolism
Autophagy / drug effects*
Calcium
Cellular Senescence / drug effects*
Disease Models, Animal
Fibroblasts / drug effects
Fibroblasts / metabolism*
Ginsenosides / metabolism*
Humans
Mice
Skin / metabolism*

Substances

Antineoplastic Agents, Phytogenic
Ginsenosides
ginsenoside Rg3
AMP-Activated Protein Kinases
Calcium

Grants and funding