Protein macrocyclization by a recombinant asparaginyl endopeptidase

Acta Biochim Biophys Sin (Shanghai). 2021 Nov 10;53(11):1567-1570. doi: 10.1093/abbs/gmab119.

Authors

Xiaoyun Hu¹, Hui Liu², Jie Li¹, Jiewen Wang¹, Wenfang Peng¹

Affiliations

¹ State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Engineering Research Center for Bio-enzyme Catalysis, Environmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-resources, School of Life Sciences, Hubei University, Wuhan 430062, China.
² Department of Hematology, Renmin Hospital of Wuhan University, Wuhan 430060, China.

PMID: 34450631
DOI: 10.1093/abbs/gmab119

No abstract available

MeSH terms

Cyclization
Cysteine Endopeptidases / biosynthesis*
Cysteine Endopeptidases / isolation & purification
Cysteine Endopeptidases / metabolism*
Peptides / chemistry
Peptides / metabolism
Proteins / chemistry*
Proteins / metabolism
Recombinant Proteins / biosynthesis*
Recombinant Proteins / isolation & purification
Recombinant Proteins / metabolism*
Saccharomycetales / genetics

Substances

Peptides
Proteins
Recombinant Proteins
Cysteine Endopeptidases
asparaginylendopeptidase

Supplementary concepts

Komagataella pastoris

Grants and funding