Serum Sickness-Like Reaction in an Adolescent Taking Minocycline for Acne

S D Med. 2021 Jul;74(7):310-313.

Abstract

We report a case of serum sickness-like reaction (SSLR) in a 14-year-old male taking minocycline for acne. The patient presented with urticarial rash, arthralgia/arthritis, and tender lymphadenopathy. Symptoms resolved with discontinuation of minocycline and treatment with prednisone, cetirizine, and ibuprofen. SSLR is a rare complication of minocycline treatment that may go unrecognized and underreported.

Publication types

  • Case Reports

MeSH terms

  • Acne Vulgaris* / drug therapy
  • Adolescent
  • Anti-Bacterial Agents / adverse effects
  • Arthralgia
  • Humans
  • Male
  • Minocycline / adverse effects
  • Serum Sickness* / chemically induced
  • Serum Sickness* / drug therapy

Substances

  • Anti-Bacterial Agents
  • Minocycline