Objective: To examine the trend of stroke disease burden and its main risk-attributable factors in China and regions with different Socio-Demographic Index (SDI) from 1990 to 2017. Methods: With 2017 Global Burden of Disease (GBD) data, years lived with disability (YLDs), years of life lost (YLLs) and disability-adjusted of life years (DALYs) were applied to describe the disease burden and major risk factors of stroke in China and different SDI regions from 1990 to 2017, and to analyze the changing trend of the disease burden and major risk factors of stroke. Results: From 1990 to 2017, the YLD crude rate, YLL crude rate and DALY crude rate for stroke in China showed an increasing trend and the rate of change was 126.5%, 14.6%, and 24.4%, respectively. In 2017, the YLD crude rate, YLL crude rate and DALY crude rate for stroke in China were 502.6 per 100 000, 2 633.1 per 100 000 and 3 135.7 per 100 000, respectively. Among them, the YLD crude rate, YLL crude rate, and DALY crude rate of stroke were the highest in the ≥70 age group, which were 2 617.2 per 100 000, 16 789.4 per 100 000 and 19 406.6 per 100 000, respectively. The YLD crude rate in male was 475.5 per 100 000, which was slightly lower than that of female (530.9 per 100 000), while the DALY crude rate and YLL crude rate for stroke were 3 657.1 per 100 000 and 3 181.7 per 100 000, respectively, which were significantly higher than that of female (2 591.8 per 100 000 and 2 060.9 per 100 000). Compared with regions with different SDI, the age standardized YLD rate, the age standardized YLL rate, the age standardized DALY rate in China were all at a high level. Among them, the age-standardized YLD rate increased from 286.2 per 100 000 to 374.5 per 100 000, with a rate of change of 30.9%; the age-standardized YLL rate decreased from 3 215.6 per 100 000 to 1 967.8 per 100 000, with a rate of change of -38.8%; the age-standardized DALY rate increased from 3 501.8 per 100 000 to 2 342.3 per 100 000, with a rate of change of -33.1%. The top five risk factors for stroke in China were hypertension, excessive sodium intake, insufficient fruit intake, insufficient cereal intake, and smoking in 1990 and 2017. High Body-Mass Index and Alcohol Use's rankings rose from the 9th and 10th in 1990 to the 6th and 7th in 2017, respectively. Conclusion: The burden of stroke disease in China is at a high level, and hypertension is the primary risk factor.
目的： 分析1990-2017年中国和不同社会人口学指数（SDI）地区脑卒中疾病负担和主要危险因素的变化趋势。 方法： 利用2017年全球疾病负担（GBD 2017）数据，采用伤残损失健康寿命年（YLDs）、早死损失寿命年（YLLs）和伤残调整寿命年（DALYs）等指标，描述1990-2017年中国和不同SDI地区脑卒中疾病负担和主要危险因素等情况，分析脑卒中疾病负担和主要危险因素的变化趋势。 结果： 1990-2017年，中国脑卒中YLD粗率、YLL粗率和DALY粗率均呈现上升趋势，变化率分别为126.5%、14.6%、24.4%。2017年中国脑卒中YLD粗率、YLL粗率和DALY粗率分别为502.6/10万、2 633.1/10万和3 135.7/10万，其中≥70岁组YLD粗率、YLL粗率、和DALY粗率最高，分别为2 617.2/10万、16 789.4/10万和19 406.6/10万。男性YLD粗率为475.5/10万，略低于女性（530.9/10万）；DALY粗率和YLL粗率分别为3 657.1/10万和3 181.7/10万，高于女性（2 591.8/10万和2 060.9/10万）。与不同SDI地区相比，1990-2017年中国脑卒中标化YLD率、标化YLL率、标化DALY率均处于高水平，其中标化YLD率由1990年的286.2/10万上升至2017年的374.5/10万，变化率为30.9%；标化YLL率由1990年的3 215.6/10万下降至2017年的1 967.8/10万，变化率为-38.8%；标化DALY率由1990年的3 501.8/10万下降至2017年的2 342.3/10万，变化率为-33.1%。1990和2017年中国脑卒中前5位危险因素分别为高血压、钠摄入过多、水果摄入不足、谷类摄入不足和吸烟，高体重指数和饮酒顺位分别由1990年的第9位和第10位上升至2017年的第6位和第7位。 结论： 中国脑卒中疾病负担处于高水平，高血压为首要危险因素。.