Lupus nephritis (LN) refers to renal involvement in systemic lupus erythematosus and is characterized by hematuria, proteinuria, edema, hypertension and renal insufficiency. The complete remission rate of proliferative LN remains low using the current induction protocols and LN tends to flare. Scientific and standardized diagnosis and therapy are crucial for the treatment of LN. Therefore, based on the current international and domestic experiences and guidelines, the Chinese Rheumatology Association developed the recommendations of diagnosis and therapy for LN, with the purpose of enhancing efficacy, reducing flare, halting renal progression and improving outcome of LN.
狼疮肾炎是系统性红斑狼疮引起的肾损害，主要表现为血尿、蛋白尿、水肿、高血压和肾功能不全等。现有的诱导治疗方案对增殖性狼疮肾炎的完全缓解率偏低，且狼疮肾炎容易复发。科学、规范地诊断和治疗狼疮肾炎十分重要。为此，中华医学会风湿病学分会在借鉴当前国内外经验和指南基础上，制定了本诊疗规范，旨在提高狼疮肾炎的疗效，减少复发，延缓肾损害的进展，改善患者预后。.