Ultrasonic Particle Manipulation in Glass Capillaries: A Concise Review

Micromachines (Basel). 2021 Jul 26;12(8):876. doi: 10.3390/mi12080876.

Abstract

Ultrasonic particle manipulation (UPM), a non-contact and label-free method that uses ultrasonic waves to manipulate micro- or nano-scale particles, has recently gained significant attention in the microfluidics community. Moreover, glass is optically transparent and has dimensional stability, distinct acoustic impedance to water and a high acoustic quality factor, making it an excellent material for constructing chambers for ultrasonic resonators. Over the past several decades, glass capillaries are increasingly designed for a variety of UPMs, e.g., patterning, focusing, trapping and transporting of micron or submicron particles. Herein, we review established and emerging glass capillary-transducer devices, describing their underlying mechanisms of operation, with special emphasis on the application of glass capillaries with fluid channels of various cross-sections (i.e., rectangular, square and circular) on UPM. We believe that this review will provide a superior guidance for the design of glass capillary-based UPM devices for acoustic tweezers-based research.

Keywords: acoustic radiation force; acoustic streaming; acoustic tweezers; glass capillary; miniaturized ultrasonic devices; ultrasonic particle manipulation.

Publication types

  • Review