Acute Plasma Cell Leukemia Presenting as Primary Hyperammonemic Encephalopathy

Dveet Patel; Andrew Mangano; David Moccia; Shawn Esperti; Kunjan Udani; Jordan Henderson; Nino Balanchivadze

doi:10.14740/jmc3559

Acute Plasma Cell Leukemia Presenting as Primary Hyperammonemic Encephalopathy

J Med Cases. 2020 Oct;11(10):320-323. doi: 10.14740/jmc3559. Epub 2020 Aug 28.

Authors

Dveet Patel^{1

2}, Andrew Mangano², David Moccia², Shawn Esperti², Kunjan Udani², Jordan Henderson², Nino Balanchivadze³

Affiliations

¹ Department of Internal Medicine, Grand Strand Health, Myrtle Beach, SC, USA.
² Affiliated Hospital of Grand Strand Medical Center, Myrtle Beach, SC, USA.
³ Department of Hematology/Oncology, Henry Ford Health System, Detroit, MI, USA.

Abstract

Primary plasma cell leukemia (PPCL) is a rare form of multiple myeloma (MM) and is a rare aggressive disease with a median overall survival of 6 - 11 months. We present a case of acute hyperammonemic encephalopathy as the initial presentation of PPCL in a 78-year-old woman to highlight an atypical presentation of this disorder.

Keywords: Hyperammonemic encephalopathy; Multiple myeloma; Plasma cell leukemia.

Publication types

Case Reports