Prevalence of Gastrointestinal Pathogens Detected by Multiplex Polymerase Chain Reaction in a Prospective Cohort of Men Who Have Sex With Men Taking Human Immunodeficiency Virus Preexposure Prophylaxis-New York City, 2019-2020

Lawrence Purpura; Jason Zucker; Elijah LaSota; Mabel Lopez; Rebecca Spicehandler; Caroline Carnevale; Edward Perez; Paul Richards; Jennifer Chang; Al Cohall; Anne-Catrin Uhlemann; Susan Whittier; Magdalena E Sobieszczyk; Daniel A Green

doi:10.1093/ofid/ofab411

Prevalence of Gastrointestinal Pathogens Detected by Multiplex Polymerase Chain Reaction in a Prospective Cohort of Men Who Have Sex With Men Taking Human Immunodeficiency Virus Preexposure Prophylaxis-New York City, 2019-2020

Open Forum Infect Dis. 2021 Aug 3;8(8):ofab411. doi: 10.1093/ofid/ofab411. eCollection 2021 Aug.

Authors

Affiliations

¹ Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
² ICAP, Mailman School of Public Health, Columbia University, New York, New York, USA.
³ Clinical Microbiology, Department of Pathology, Columbia University Irving Medical Center, New York, New York, USA.
⁴ New York Presbyterian-Columbia Hospital, New York, New York, USA.

Abstract

Multiplex polymerase chain reaction testing for gastrointestinal pathogens was performed on a longitudinal cohort of 110 men who have sex with men taking human immunodeficiency virus preexposure prophylaxis. At least 1 pathogen was detected among 50 (45%) participants, with some participants testing positive for the same pathogen on multiple consecutive visits over a period of months.

Keywords: gastrointestinal pathogen; men who have sex with men; polymerase chain reaction; preexposure prophylaxis.

Abstract

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