Peuzt - Jeghers syndrome with gastric type mucinous endocervical adenocarcinoma in a young woman: A case report

Giap Vu Dinh; Nhat Doan Thi Hong; Tu Vo Ngoc; Long Nguyen Thanh; Hoai Hoang Thi; Huyen Phung Thi

doi:10.1016/j.amsu.2021.102700

Peuzt - Jeghers syndrome with gastric type mucinous endocervical adenocarcinoma in a young woman: A case report

Ann Med Surg (Lond). 2021 Aug 10:69:102700. doi: 10.1016/j.amsu.2021.102700. eCollection 2021 Sep.

Authors

Giap Vu Dinh¹, Nhat Doan Thi Hong², Tu Vo Ngoc¹, Long Nguyen Thanh³, Hoai Hoang Thi³, Huyen Phung Thi⁴

Affiliations

¹ Department of Breast and Gynecologic Surgical Oncology, Nghe An Oncology Hospital, Nghe An, Viet Nam.
² Deapartment of Clinical Surgery, Vinh Medical University, Nghe An, Viet Nam.
³ Department of Oncology, Hanoi Medical University, Hanoi, Viet Nam.
⁴ Department of Medical Oncology 6, Vietnam National Cancer Hospital, Hanoi, Viet Nam.

Abstract

Introduction: Patients with Peutz-Jeghers syndrome (PJS) have high risk of malignancies, including gynecological cancers. Gastric type mucinous cervical adenocarcinoma might be presented in about 11-17% of PJS patients but the literature about this is limited.

Case presentation: We presented a rare case of a 39-year-old Vietnamese woman with Peutz-Jeghers syndrome who has gastric type adenocarcinoma (GAS) of the cervix. She underwent radical hysterectomy, and the diagnosis was confirmed on final pathology.

Conclusions: Oncologists and pathologists should recognize this rare clinical scenario for early diagnosis and treatment. This subtype also has an aggressive nature and poor prognosis.

Keywords: Adenocarcinoma; Case report; Gastric type mucinous endocervical adenocarcinoma; Peutz-Jeghers syndrome.

Publication types

Case Reports