An Eggshell-Based Toothpaste as a Cost-Effective Treatment of Dentin Hypersensitivity

Ensanya A Abou Neel; Turki A Bakhsh

doi:10.1055/s-0041-1729676

An Eggshell-Based Toothpaste as a Cost-Effective Treatment of Dentin Hypersensitivity

Eur J Dent. 2021 Oct;15(4):733-740. doi: 10.1055/s-0041-1729676. Epub 2021 Aug 24.

Authors

Ensanya A Abou Neel^{1

2

3}, Turki A Bakhsh⁴

Affiliations

¹ Department of Preventive and Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah, United Arab Emirates.
² Department of Biomaterials, Faculty of Dentistry, Tanta University, Tanta, Egypt.
³ Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, Royal Free Hospital, UCL Medical School, Hampstead, London, United Kingdom.
⁴ Department of Restorative Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.

Abstract

Objectives: This study aimed to test the efficacy of two experimentally produced eggshell-based toothpastes on dentinal tubules occlusion.

Materials and methods: Two experimental eggshell toothpastes, based on natural ingredients, with or without titanium dioxide nanoparticles (TNPs) were produced and coded "TNPs eggshell toothpaste [TNPsESTP]" or "eggshell toothpaste [ESTP]," respectively. Mid-coronal dentin discs, from 28 human extracted molar teeth, etched with 37% phosphoric acid for 60 seconds to simulate the hypersensitive dentin, were randomly divided into four groups-G1: no treatment (negative control), G2: ESTP treated, G3: TNPsESTP treated, and G4: Biorepair treated (positive control). All treated discs were brushed for 2 weeks and 1 month using a toothbrush simulator at 40 mm/s. Dentinal tubules occlusion was studied using a cross-polarization optical coherence tomography (CP-OCT) and scanning electron microscopy (SEM).

Statistical analysis: Unpaired t-test was conducted using GraphPad software (San Diego, California, United States). Continuous variables were expressed as means ± standard deviation and p < 0.05 was considered statistically significant.

Results: From CP-OCT, a marked increase in surface reflectivity of dentin was observed after brushing with tested toothpastes. ESTP and NPsESTP showed higher or comparable grayscale values than Biorepair indicating increase in surface density of dentin. From SEM, at 2 weeks, ESTP showed comparable number of completely occluded dentinal tubules to Biorepair. TNPsESTP showed significantly lower numbers of CODT than Biorepair. At 1 month, the number of CODT was difficult to count for all treated groups. Both ESTP and TNPsESTP showed significantly higher numbers of partially occluded dentinal tubules than Biorepair.

Conclusion: ESTP or TNPsESTP could offer a cost-effective substitute for the treatment of dentin hypersensitivity.

European Journal of Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).