The Sugars in Alcohol Cocktails Matter

ACS Chem Neurosci. 2021 Sep 15;12(18):3284-3287. doi: 10.1021/acschemneuro.1c00526. Epub 2021 Aug 24.

Abstract

While sugar consumption and alcohol drinking have traditionally been studied by different basic science fields, most commercially available flavored alcoholic beverages are sweetened with some kind of sugar. The prevailing view is that these sugars potentiate drinking by making the alcohol taste better, particularly for adolescents, overlooking that some central nervous system circuits implicated in alcohol drinking are also sensitive to brain penetrant sugars like glucose. In this Viewpoint, we highlight the need for basic researchers to carefully consider how the sugars mixed with alcoholic beverages may impact the neurochemical and biological mechanisms influencing alcohol drinking and the development of alcohol use disorder.

Keywords: Sugar consumption; alcohol drinking; alcohol use disorder; brain penetrant sugars; central nervous system; flavored alcoholic beverages.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Alcohol Drinking
  • Alcoholic Beverages*
  • Ethanol
  • Humans
  • Sugars*
  • Taste

Substances

  • Sugars
  • Ethanol