Gram-Negative Bacteria Harboring Multiple Carbapenemase Genes, United States, 2012-2019

Emerg Infect Dis. 2021;27(9):2475-2479. doi: 10.3201/eid2709.210456.

Abstract

Reports of organisms harboring multiple carbapenemase genes have increased since 2010. During October 2012-April 2019, the Centers for Disease Control and Prevention documented 151 of these isolates from 100 patients in the United States. Possible risk factors included recent history of international travel, international inpatient healthcare, and solid organ or bone marrow transplantation.

Keywords: AMR; Acinetobacter baumannii; Enterobacteriaceae; Pseudomonas; United States; antimicrobial resistance; carbapenem-resistant Enterobacterales; carbapenemase; carbapenems; drug resistance; resistance genes.

MeSH terms

  • Bacterial Proteins* / genetics
  • Gram-Negative Bacteria
  • Humans
  • United States / epidemiology
  • beta-Lactamases* / genetics

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase