Immunological changes after COVID-19 vaccination in an HIV-positive patient

Changlin Gong; Xiaojing Song; Xiaoxia Li; Lianfeng Lu; Taisheng Li

doi:10.1016/j.ijid.2021.08.039

Immunological changes after COVID-19 vaccination in an HIV-positive patient

Int J Infect Dis. 2022 Apr:117:230-232. doi: 10.1016/j.ijid.2021.08.039. Epub 2021 Aug 19.

Authors

Changlin Gong¹, Xiaojing Song¹, Xiaoxia Li¹, Lianfeng Lu¹, Taisheng Li²

Affiliations

¹ Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
² Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. Electronic address: litsh@263.net.

Abstract

Vaccination is an essential measure to stop the coronavirus disease 2019 (COVID-19) pandemic. We report a case of viral activation and CD4+ T cell loss in a treatment-naïve HIV-positive patient after receiving inactivated COVID-19 vaccine (Sinopharm). The vaccine should probably be given only to people living with HIV receiving antiretroviral therapy.

Keywords: CD4+ T cells; Coronavirus disease 2019; Human immunodeficiency virus; Vaccine.

Publication types

Case Reports

MeSH terms

CD4-Positive T-Lymphocytes
COVID-19 Vaccines
COVID-19* / prevention & control
HIV Infections* / complications
HIV Infections* / drug therapy
Humans
Vaccination

Substances

COVID-19 Vaccines