Building a complex for destruction

Anton J Venhuizen; Felix van der Krift; Madelon M Maurice

doi:10.1016/j.molcel.2021.07.032

Building a complex for destruction

Mol Cell. 2021 Aug 19;81(16):3241-3243. doi: 10.1016/j.molcel.2021.07.032.

Authors

Anton J Venhuizen¹, Felix van der Krift¹, Madelon M Maurice²

Affiliations

¹ Center for Molecular Medicine, University Medical Center Utrecht, the Netherlands; Oncode Institute, the Netherlands.
² Center for Molecular Medicine, University Medical Center Utrecht, the Netherlands; Oncode Institute, the Netherlands. Electronic address: m.m.maurice@umcutrecht.nl.

PMID: 34416136
DOI: 10.1016/j.molcel.2021.07.032

Abstract

Ranes et al. (2021) report on an in vitro reconstituted β-catenin destruction complex and elucidate the contributions of full-length and cancer-related mutated core components to β-catenin turnover, thereby advancing our understanding of the inner workings of this tumor suppressor complex.

Publication types

Comment